{"id":10636,"date":"2026-04-10T18:24:39","date_gmt":"2026-04-10T15:24:39","guid":{"rendered":"http:\/\/biotech.nahrainuniv.edu.iq\/?p=10636"},"modified":"2026-04-10T18:24:41","modified_gmt":"2026-04-10T15:24:41","slug":"%d9%85%d9%86%d8%a7%d9%82%d8%b4%d8%a9-%d8%b1%d8%b3%d8%a7%d9%84%d8%a9-%d9%85%d8%a7%d8%ac%d8%b3%d8%aa%d9%8a%d8%b1-21","status":"publish","type":"post","link":"http:\/\/biotech.nahrainuniv.edu.iq\/?p=10636","title":{"rendered":"\u0645\u0646\u0627\u0642\u0634\u0629 \u0631\u0633\u0627\u0644\u0629 \u0645\u0627\u062c\u0633\u062a\u064a\u0631"},"content":{"rendered":"\n<p class=\"has-text-align-right\">&#8220;\u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0642\u0646\u064a\u0627\u062a \u0627\u0644\u0623\u062d\u064a\u0627\u0626\u064a\u0629 \u062a\u0646\u0627\u0642\u0634 \u0631\u0633\u0627\u0644\u0629 \u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u062d\u0648\u0644 \u062f\u0648\u0631 \u0627\u0644\u0640 circRNA \u0641\u064a \u062a\u0646\u0638\u064a\u0645 \u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0644\u0648\u0643\u064a\u0645\u064a\u0627&#8221;<\/p>\n\n\n\n<p class=\"has-text-align-right\">\u0634\u0647\u062f\u062a \u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0642\u0646\u064a\u0627\u062a \u0627\u0644\u0623\u062d\u064a\u0627\u0626\u064a\u0629 \u0645\u0646\u0627\u0642\u0634\u0629 \u0631\u0633\u0627\u0644\u0629 \u0627\u0644\u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u0644\u0644\u0628\u0627\u062d\u062b\u0629 \u062f\u0627\u0646\u064a\u0629 \u0639\u0645\u0631 \u0639\u062f\u0646\u0627\u0646\u060c \u0648\u0627\u0644\u062a\u064a \u062c\u0627\u0621\u062a \u0628\u0639\u0646\u0648\u0627\u0646:\u201cInvestigation the role of circular RNA in modulating CD8 T cells responses in acute myeloid leukemia.\u201d\u0648\u0647\u062f\u0641\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0625\u0644\u0649 \u062a\u0642\u064a\u064a\u0645 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u064a \u0644\u0643\u0644 \u0645\u0646 circ_0001068 \u0648 circ_0002178 \u0648 miR-28-5p \u0648 miR-34a-5p \u0644\u062f\u0649 \u0645\u0631\u0636\u0649 \u0627\u0628\u064a\u0636\u0627\u0636 \u0627\u0644\u062f\u0645 \u0627\u0644\u0646\u0642\u0648\u064a \u0627\u0644\u062d\u0627\u062f (AML) \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0627\u0644\u0623\u0634\u062e\u0627\u0635 \u0627\u0644\u0623\u0635\u062d\u0627\u0621\u060c \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062a\u0642\u0646\u064a\u0629 qRT-PCR\u060c \u0645\u0639 \u062a\u062d\u0644\u064a\u0644 \u0639\u0644\u0627\u0642\u062a\u0647\u0627 \u0628\u0646\u0634\u0627\u0637 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062a\u0627\u0626\u064a\u0629 \u0627\u0644\u0633\u0627\u0645\u0629 CD8\u207a \u0648\u062f\u0648\u0631\u0647\u0627 \u0641\u064a \u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0636\u062f \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0644\u0648\u0643\u064a\u0645\u064a\u0627.\u0643\u0645\u0627 \u062a\u0636\u0645\u0646\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u062a\u062d\u0644\u064a\u0644 \u0645\u0624\u0634\u0631\u0627\u062a \u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062a\u0627\u0626\u064a\u0629 CD25 \u0648 CD69 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062a\u0642\u0646\u064a\u0629 \u0627\u0644\u062a\u062f\u0641\u0642 \u0627\u0644\u062e\u0644\u0648\u064a (Flow Cytometry)\u060c \u0625\u0636\u0627\u0641\u0629\u064b \u0625\u0644\u0649 \u0642\u064a\u0627\u0633 \u0625\u0641\u0631\u0627\u0632 \u0627\u0644\u062c\u0632\u064a\u0626\u0627\u062a \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 IFN-\u03b3 \u0648 Granzyme B \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062a\u0642\u0646\u064a\u0629 ELISA.\u0648\u0623\u0638\u0647\u0631\u062a \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0648\u062c\u0648\u062f \u062a\u063a\u064a\u0631\u0627\u062a \u0645\u0639\u0646\u0648\u064a\u0629 \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0644\u0628\u0639\u0636 circRNAs \u0648 miRNAs \u0644\u062f\u0649 \u0645\u0631\u0636\u0649 AML\u060c \u0641\u0636\u0644\u0627\u064b \u0639\u0646 \u062a\u0633\u062c\u064a\u0644 \u0627\u0646\u062e\u0641\u0627\u0636 \u0641\u064a \u0643\u0641\u0627\u0621\u0629 \u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0644\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062a\u0627\u0626\u064a\u0629 \u0627\u0644\u0633\u0627\u0645\u0629\u060c \u0628\u062d\u0633\u0628 \u0646\u062a\u0627\u0626\u062c Flow Cytometry \u0648 ELISA\u060c \u0645\u0645\u0627 \u064a\u0634\u064a\u0631 \u0625\u0644\u0649 \u062d\u062f\u0648\u062b \u062d\u0627\u0644\u0629 \u0645\u0646 \u0627\u0644\u0625\u062c\u0647\u0627\u062f \u0627\u0644\u0648\u0638\u064a\u0641\u064a \u0644\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062a\u0627\u0626\u064a\u0629 (T-cell exhaustion)\u060c \u0648\u0647\u0648 \u0645\u0627 \u0642\u062f \u064a\u0636\u0639\u0641 \u0642\u062f\u0631\u062a\u0647\u0627 \u0639\u0644\u0649 \u0627\u0644\u0642\u0636\u0627\u0621 \u0639\u0644\u0649 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0644\u0648\u0643\u064a\u0645\u064a\u0627.\u0648\u062a\u0624\u0643\u062f \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0623\u0647\u0645\u064a\u0629 \u0647\u0630\u0647 \u0627\u0644\u062c\u0632\u064a\u0626\u0627\u062a \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629 \u0643\u0645\u0624\u0634\u0631\u0627\u062a \u062d\u064a\u0648\u064a\u0629 \u0648\u0627\u0639\u062f\u0629\u060c \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0633\u0647\u0645 \u0641\u064a \u0641\u0647\u0645 \u0623\u0639\u0645\u0642 \u0644\u0644\u0622\u0644\u064a\u0627\u062a \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u0629 \u0648\u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0645\u0631\u0636 AML\u060c \u0641\u0636\u0644\u0627\u064b \u0639\u0646 \u062f\u0639\u0645 \u062a\u0637\u0648\u064a\u0631 \u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0627\u062a \u062a\u0634\u062e\u064a\u0635\u064a\u0629 \u0648\u0639\u0644\u0627\u062c\u064a\u0629 \u0645\u0633\u062a\u0642\u0628\u0644\u064a\u0629.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292971.jpg\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"768\" src=\"http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292971-1024x768.jpg\" alt=\"\" class=\"wp-image-10637\" srcset=\"http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292971-1024x768.jpg 1024w, http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292971-300x225.jpg 300w, http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292971-768x576.jpg 768w, http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292971-1536x1152.jpg 1536w, http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292971-1568x1176.jpg 1568w, http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292971.jpg 1600w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><a href=\"http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292972.jpg\"><img decoding=\"async\" width=\"1024\" height=\"643\" data-id=\"10638\" src=\"http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292972-1024x643.jpg\" alt=\"\" class=\"wp-image-10638\" srcset=\"http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292972-1024x643.jpg 1024w, http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292972-300x188.jpg 300w, http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292972-768x482.jpg 768w, http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292972-1536x964.jpg 1536w, http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292972-1568x984.jpg 1568w, http:\/\/biotech.nahrainuniv.edu.iq\/wp-content\/uploads\/2026\/04\/1000292972.jpg 1600w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n<\/figure>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;\u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0642\u0646\u064a\u0627\u062a \u0627\u0644\u0623\u062d\u064a\u0627\u0626\u064a\u0629 \u062a\u0646\u0627\u0642\u0634 \u0631\u0633\u0627\u0644\u0629 \u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u062d\u0648\u0644 \u062f\u0648\u0631 \u0627\u0644\u0640 circRNA \u0641\u064a \u062a\u0646\u0638\u064a\u0645 \u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0644\u0648\u0643\u064a\u0645\u064a\u0627&#8221; \u0634\u0647\u062f\u062a \u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0642\u0646\u064a\u0627\u062a \u0627\u0644\u0623\u062d\u064a\u0627\u0626\u064a\u0629 \u0645\u0646\u0627\u0642\u0634\u0629 \u0631\u0633\u0627\u0644\u0629 \u0627\u0644\u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u0644\u0644\u0628\u0627\u062d\u062b\u0629 \u062f\u0627\u0646\u064a\u0629 \u0639\u0645\u0631 \u0639\u062f\u0646\u0627\u0646\u060c \u0648\u0627\u0644\u062a\u064a \u062c\u0627\u0621\u062a \u0628\u0639\u0646\u0648\u0627\u0646:\u201cInvestigation the role of circular RNA in modulating CD8 T cells responses in acute myeloid leukemia.\u201d\u0648\u0647\u062f\u0641\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0625\u0644\u0649 \u062a\u0642\u064a\u064a\u0645 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u064a \u0644\u0643\u0644 \u0645\u0646 circ_0001068 \u0648 &hellip; <\/p>\n<p class=\"link-more\"><a href=\"http:\/\/biotech.nahrainuniv.edu.iq\/?p=10636\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;\u0645\u0646\u0627\u0642\u0634\u0629 \u0631\u0633\u0627\u0644\u0629 \u0645\u0627\u062c\u0633\u062a\u064a\u0631&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1113,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27,44,49],"tags":[],"class_list":["post-10636","post","type-post","status-publish","format-standard","hentry","category-uncategorized-ar","category-44","category-49","entry"],"_links":{"self":[{"href":"http:\/\/biotech.nahrainuniv.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/10636","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/biotech.nahrainuniv.edu.iq\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biotech.nahrainuniv.edu.iq\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biotech.nahrainuniv.edu.iq\/index.php?rest_route=\/wp\/v2\/users\/1113"}],"replies":[{"embeddable":true,"href":"http:\/\/biotech.nahrainuniv.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=10636"}],"version-history":[{"count":1,"href":"http:\/\/biotech.nahrainuniv.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/10636\/revisions"}],"predecessor-version":[{"id":10639,"href":"http:\/\/biotech.nahrainuniv.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/10636\/revisions\/10639"}],"wp:attachment":[{"href":"http:\/\/biotech.nahrainuniv.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=10636"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biotech.nahrainuniv.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=10636"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biotech.nahrainuniv.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=10636"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}